Vaccination and passive immunisation schedule

Routine vaccination is a way of ensuring individual and collective protection. Vaccines protect us against certain infectious diseases and their impacts on our health.

In Luxembourg, vaccine recommendations are drawn up by the Superior Council of Infectious Diseases (Conseil supérieur des maladies infectieuses - CSMI) and implemented by the Health Directorate, which proposes the following vaccination schedule.

The recommendations relate to infants and young children, children, adolescents and adults.

PREGNANT WOMEN 
During pregnancy 
  1. Flu: in winter, using an inactivated vaccine, regardless of the stage of pregnancy.
  2. COVID-19: for pregnant women (Pdf, 54 Kb) with additional risk factors that predispose them to severe COVID-19 outcomes.

2nd and 3rd 

trimester
  1. Whooping cough: ideally during the 2nd trimester, but also up to the 26th week of pregnancy (or 2 weeks before the birth at the latest) using a combined dTap or dTap/IPV vaccine.

32nd - 36th

week of pregnancy
  1. RSV (respiratory syncytial virus): vaccination of pregnant women who are in good health and have a healthy pregnancy; the vaccine is administered during the peak season for the virus, i.e. from September to February.1

1 Alternatively, a preventive treatment may be administered to the newborn (see below).

INFANTS AND YOUNG CHILDREN
(specific recommendations apply to children born prematurely - you can find them here (PDF, 784 Kb) (Pdf, 784 Kb))
Newborns
  1. RSV (respiratory syncytial virus): administration of a preventive treatment (passive immunisation product) offering protection against bronchiolitis, ideally before discharge from the maternity ward, during the peak season for the virus, i.e. from September to February.
2 months
  1. 1st dose of the combined vaccine (DTaP, Hib, IPV, Hep B), which offers protection against:
    • diphtheria,
    • tetanus,
    • whooping cough,
    • invasive Haemophilus influenzae type b infections (meningitis, epiglottitis and arthritis),
    • polio,
    • hepatitis B.
  2. Rotavirus (1st dose): vaccination against rotavirus gastroenteritis.
  3. Pneumococcus (1st dose): vaccination against invasive pneumococcal infections.

3 months 
  1. Rotavirus (2nd dose): vaccination against rotavirus gastroenteritis.
  2. Meningococcus B (1st dose): vaccination against invasive meningococcal B infections.
  3. Pneumococcus (2nd dose): vaccination against invasive pneumococcal infections

4 months 
  1. 2nd dose of the combined vaccine (DTaP, Hib, IPV, Hep B), which offers protection against:
    • diphtheria,
    • tetanus,
    • whooping cough,
    • invasive Haemophilus influenzae type b infections (meningitis, epiglottitis and arthritis),
    • polio,
    • hepatitis B.
  2. Pneumococcus (3rd dose): vaccination against invasive pneumococcal infections.
  3. Rotavirus (3rd dose): vaccination against rotavirus gastroenteritis.

5 months
  1. Meningococcus B (2nd dose): vaccination against invasive meningococcal B infections.
Up to
6 months 
  1. RSV: for infants under 6 months old who have not received it before being discharged from the maternity ward, administration of a preventive treatment (passive immunisation product) offering protection against bronchiolitis, during the peak season for the virus, i.e. from September to February.

11 months
  1. 3rd dose of the combined vaccine (DTaP, Hib, IPV, Hep B), which offers protection against:
    • diphtheria,
    • tetanus,
    • whooping cough,
    • invasive Haemophilus influenzae type b infections (meningitis, epiglottitis and arthritis),
    • polio,
    • hepatitis B.
  2. Pneumococcus (4th dose): vaccination against invasive pneumococcal infections.

12 months 
  1. 1st dose of the combined vaccine (MMRV), which offers protection against:
    • measles,
    • mumps,
    • rubella,
    • chickenpox.
  2. Meningococcus B (3rd dose): vaccination against invasive meningococcal B infections.

13 months 
  1. Meningococcus ACWY (1st dose): vaccination against invasive meningococcal A, C, W and Y infections.

15-23 months 
  1. 2nd dose of the combined vaccine (MMRV), which offers protection against:
    • measles,
    • mumps,
    • rubella,
    • chickenpox.
CHILDREN AND ADOLESCENTS
ages 2-17
  1.  Seasonal flu: vaccination before the winter period (available since 15 October 2025)
ages 5-6
  1. Combined booster vaccine (DTaP/IPV), which offers protection against:
    • diphtheria,
    • tetanus,
    • whooping cough,
    • polio.
  2. Catch-up vaccination against invasive pneumococcal infections for vulnerable, unvaccinated children.
ages 9-14
  1. Human papillomavirus (HPV): vaccination of girls and boys against human papillomavirus infections (2 doses).
ages 12-18
  1. Catch-up vaccination against hepatitis B for unvaccinated children.
ages 15-20
  1. Combined booster vaccine (DTaP/IPV), which offers protection against:
    • diphtheria,
    • tetanus,
    • whooping cough,
    • polio.
  2. Booster vaccine against invasive meningococcal ACWY infections.
  3. Catch-up vaccination against human papillomavirus (HPV) infections for unvaccinated adolescents.
ADULTS
Every 10 years
  1. Combined booster vaccine (DTaP/IPV), which offers protection against:
    • diphtheria,
    • tetanus,
    • whooping cough,
    • polio.
  2. For adults born after 1980 who have not received 2 doses of the measles, mumps and rubella vaccine, a booster dose of this vaccine is recommended.
age 65 and above
  1. Vaccination against invasive pneumococcal infections.
  2. Vaccination against seasonal influenza.
  3. Vaccination against shingles.
  4. Seasonal vaccination against COVID-19.

The costs of vaccinations recommended as part of the national vaccination programme are covered by the State.

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